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5-ALA benzyl ester hydrochloride

CAS No. 163271-32-7

5-ALA benzyl ester hydrochloride( Benzyl-ALA hydrochloride )

Catalog No. M27058 CAS No. 163271-32-7

5-ALA benzyl ester hydrochloride is a protoporphyrin precursor and can be used as a photodetection agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    5-ALA benzyl ester hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    5-ALA benzyl ester hydrochloride is a protoporphyrin precursor and can be used as a photodetection agent.
  • Description
    5-ALA benzyl ester hydrochloride is a protoporphyrin precursor and can be used as a photodetection agent.(In Vitro):In colon carcinoma cell lines SW480, 5-ALA benzyl ester hydrochloride (0.6-0.12 mM; 3h) induces PPIX accumulation.(In Vivo):In female CBA/Gy mice, 5-ALA benzyl ester hydrochloride (31 mg/kg; i.v.; 1h) results in a dose-dependent reduction in tumour porphyrin levels.
  • In Vitro
    5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) (0.6-0.12 mM; 3 h) induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines SW480.
  • In Vivo
    Reducing the dose of 5-ALA benzyl ester hydrochloride (31 mg/kg; i.v. ; 1 hours) results in a dose-dependent reduction in tumour porphyrin levels. Animal Model:Female CBA/Gy mouse (CaNT tumour model)Dosage:31 mg/kg Administration:i.v. ; 1 hours Result:Reducing the dose of 5-ALA benzyl ester hydrochloride resulted in a dose-dependent reduction in the concentration of porphyrins accumulating in the CaNT tumour.
  • Synonyms
    Benzyl-ALA hydrochloride
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Cytochrome C
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    163271-32-7
  • Formula Weight
    257.71
  • Molecular Formula
    C12H16ClNO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (970.08 mM)
  • SMILES
    Cl.NCC(=O)CCC(=O)OCc1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Santucci R, et al. Cytochrome c: An extreme multifunctional protein with a key role in cell fate. Int J Biol Macromol. 2019 Sep 1;136:1237-1246.
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